RESULTS The MiCheck logistic regression model was developed and comprises the following variables serum prostate-specific antigen (PSA), patient age, Digital Rectal Exam (DRE) status, Leptin, IL-7, vascular endothelial growth factor, and Glypican-1. The model differentiated AgCaP from non-AgCaP with an area under the curve of 0.83 and was superior…[Read more]

Background Stroke burden in young adults is growing associated with unique risk factors and devastating outcomes. We aimed to investigate the magnitude, risk factors and outcomes of first ever stroke in young adults ≤45 years compared to older adults > 45 years. Methods All patients with a World Health Organization clinical definition of stroke a…[Read more]

Despite next-generation sequencing, which now allows for the accurate detection of segmental aneuploidies from in vitro fertilization embryo biopsies, the origin and characteristics of these aneuploidies are still relatively unknown. Using a multifocal biopsy approach (four trophectoderms [TEs] and one inner cell mass [ICM] analyzed per…[Read more]

Background Since it was assumed that exercise might be a risk factor for upper respiratory tract infection (URTI), the frequency, severity and duration of URTI were assessed in female elite runners compared with matched sedentary group. Methods Oone group of elite runners (n = 20) and sedentary people (n = 20) selected and were matched one by one…[Read more]

Since cardiolipin, ATP synthase dimers, the MICOS complex, and dynamin-like Opa1/Mgm1 are known to be involved in shaping cristae, we examined their variation in the context of crista diversity. Moreover, we have identified both commonalities and differences that may collectively be manifested as diverse variations of crista form and…[Read more]