Furthermore, KLF16 expression was correlated with MYC signaling activity. Conclusion KLF16 was overexpressed in PCa tissues compared to normal tissues. KLF16 knockdown suppressed PCa cell growth in vitro and in vivo, and a deficiency of KLF16 inhibited activation of MYC signaling. © 2020 Zhang et al.Background Acute myeloid leukemia (AML) is a…[Read more]

Unmanned Aerial Systems (UAS) are widely used in low-cost photogrammetry. Even small Unmanned Aerial Vehicles (UAV) can deliver valuable data for the inventory of inaccessible and dangerous areas or objects. The acquisition of data for 3D object modeling is a complicated, time-consuming, and cost-intensive process. It requires the use of expensive…[Read more]

In this study, the role and mechanism of pterostilbene (Pts) in mast cell degranulation in vitro and in vivo were investigated. The results showed that Pts inhibited mast cell-mediated local passive allergic reactions in mice. In addition, treatment with Pts reduced both histamine release and calcium influx in rat peritoneal mast cells and RBL-2H3…[Read more]

We present MAPSYNE, a miniaturized and automated system combining a high-density microelectrode array (HD-MEA) and a movable micropipette for studying, monitoring, and perturbing neurons in vitro. The system involves an all-electrical approach to automatically move a glass micropipette towards a target location on the HD-MEA surface, without the…[Read more]

Evidence of the involvement of epigenetics in pathologies such as cancer, diabetes, and neurodegeneration has increased global interest in epigenetic modifications. For nearly thirty years, it has been known that cancer cells exhibit abnormal DNA methylation patterns. In contrast, the large-scale analysis of histone post-translational…[Read more]