Surgeons have shifted away from the practice of en bloc esophagectomy, particularly in the era of neoadjuvant therapies. While some still advocate for this radical approach, contemporary data which establish its superiority are sparse. We hypothesized that a more complete, radical resection could be completed in the setting of chemoradiation…[Read more]

ing a period of 5.5 years. Moving forward, greater investigation of program usage, development, and efficacy is necessary. Level of evidence Level II therapeutic. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.Background The use of tranexamic acid (TXA)…[Read more]

The implications of ablation for atrial fibrillation in preventing stroke are controversial, and no studies have investigated whether ablation prevents ischaemic stroke (IS) in atrial flutter (AFL).

This study analysed data contained in the Taiwan National Health Insurance Research Database for 16765 patients with a first diagnosis of…[Read more]

Multiple C-H bond functionalizations promptly install diverse groups on the molecular framework and consequently fabricate complex molecular entities. This review briefly surveys the conceptual development of directing group assisted unsymmetrical multiple functionalization of arene C(sp2 )-H bonds, which is exceedingly appealing and highly…[Read more]

Conversely, advice that prevented harm was provided by only 17.3% (n=19) pharmacists and 10.9% (n=12) pharmacy assistants. History-taking was not attempted by 84 pharmacy staff.

The majority of pharmacy staff involved in this study did not manage a request for a CM with known drug-herb interactions in a way that would prevent harm. These…[Read more]