• Hoffmann Brodersen posted an update 1 month, 3 weeks ago

    This study represents the first attempt to describe ultrastructural features of teeth in different three ages of white grouper (Epinephelus aeneus) grossly and by the aid of the electron microscope. The current study depends on 18 oropharyngeal cavity of E. aeneus from each age-stages. There are common and special characterization between each age. Five teeth bands in the roof (incisive, canine, upper molar, palatine, and vomer), while two bands in the floor (incisive, molar). The apical teeth part resembles the arrowhead that bordered by groove distally. In 5 cm age, small upper incisive teeth had two appearance (straight and curved), and vomer teeth arranged in triangular in only one row (while, in 12 cm fish arranged in two rows and in 15 cm fish arranged in more than two rows), the palatine teeth began rostrally as one row then two rows and terminated by one row, while in other two ages began by two, then three and ended by two rows. There is no canine teeth in lower jaw in all age. In 12 cm fish, the rostral row of lower incisive teeth usually contain small straight teeth, while the posterior row mainly contain large with some medium upper incisive teeth. In 18 cm fish, upper incisive teeth located within two incisive fossa that separated from each other by longitudinal part of T-shaped upper incisive ridge and small incisive teeth had two appearance (straight and curved), and each canined teeth group contain four teeth (while in other two ages each group contain only two canine teeth).

    Sexual health, wellbeing, and function are important parts of a person’s identity. Chronic diseases, such as kidney failure can alter, impair, and profoundly, affect sexual wellbeing and function.

    To conduct a scoping review of studies about renal nurses’ practice and attitudes towards sexual health, wellbeing, and function in people with kidney failure receiving haemodialysis.

    Using Arksey and O’Malley’s framework, seven databases were searched (CINAHL, MEDLINE, EMBASE, OvidPsycINFO, Scopus, Cochrane library, and JBI library). The search included studies published in English from January 2009 to January 2020.

    Four studies met the review criteria (two cross-sectional surveys and two qualitative). Role confusion in discussing sexual issues, lack of training, and education in addressing sexual concerns, personal, and workplace related barriers were four factors that emerged from the review of the studies. This review identified that renal nurses were uncomfortable and hesitant in initiating discussions about sexual health, wellbeing, and function with people receiving haemodialysis.

    Renal nurses experience role confusion about whose responsibility it is to initiate and discuss sexual concerns with patients, as well as who’s role is it to conduct sexual health assessments. Work related and personal barriers impeded nurses’ practice regarding sexual health, wellbeing, and function. Nurses working in renal units need knowledge and practical training about how to initiate and address sexual concerns in those affected by kidney disease.

    Renal nurses experience role confusion about whose responsibility it is to initiate and discuss sexual concerns with patients, as well as who’s role is it to conduct sexual health assessments. Work related and personal barriers impeded nurses’ practice regarding sexual health, wellbeing, and function. Nurses working in renal units need knowledge and practical training about how to initiate and address sexual concerns in those affected by kidney disease.Studies regarding the neoplastic infiltration of the skin overlying canine subcutaneous soft tissue sarcoma (sSTS) are lacking. In case of the absence of tumor infiltration, there would be the possibility of leaving this unaffected skin in place, thus simplifying surgery. The aim of the study was to investigate whether the skin overlying sSTSs is infiltrated by neoplastic cells. Dogs with sSTSs treated surgically were prospectively enrolled. After excision, the skin was dissected from the tumor along the natural surgical plane of cleavage and histologically evaluated. Twenty-nine dogs with an sSTS were included (22 grade I, 6 grade II, and 1 grade III). The sSTS-overlying skin was not tumor-infiltrated in 14/29 cases (48.3%). A higher frequency of infiltration was observed in higher grade sSTSs (grades II and III, 100%; P = .006); nevertheless, 8/22 grade I sSTSs (36%) also showed cutaneous infiltration. This infiltration involved the dermis of the skin directly in contact with the tumor (multifocal in 11 and diffuse in four cases). Although the cutaneous tumor infiltration is less frequent in grade I sSTSs and a wide excision may still be the safest treatment for any sSTS for a greater possibility of local control, this study opens the possibility to a less aggressive cutaneous excision, but still with a local curative intent, as only the skin directly in contact with the sSTS has been proven to be tumor-infiltrated. Additional studies are warranted to confirm that excision of only this skin may guarantee a complete local control, especially in lower-grade sSTSs.

    Long non-coding RNAs (lncRNAs) play important roles in the regulation of biological processes and have been identified in many species including insects. However, the association between lncRNAs and pesticide resistance in insect species such as Bactrocera dorsalis is unknown.

    RNA-seq was performed on malathion resistant (MR1) and susceptible (MS) strains of B. dorsalis and a total of 6171 lncRNAs transcripts were identified. These included 3728 lincRNAs, 653 antisense lncRNAs, 1402 intronic lncRNAs, and 388 sense lncRNAs. NU7026 cost A total of 40 and 52 upregulated lncRNAs were found in females and males of the MR1 strain compared to 54 and 49 in the same sexes of the MS strain, respectively. Twenty-seven of these lncRNAs showed the same trend of expression in both females and males in the MR1 strain, in which 15 lncRNAs were upregulated and 12 were downregulated. RT-qPCR results indicated that the differentially expressed lncRNAs were associated with malathion resistance. The lnc15010.10 and lnc3774.2 were highly expressed in the cuticle of the MR1 strain, indicating that these two lncRNAs may be related to malathion resistance.