Further analysis found differences in the variance in axial length growth (P < 0.0001) between operated and normal eyes; the variance in keratometry measurement change did not reach significance.

The standard deviation in the rate of refractive growth of normal eyes in our study is half of that found in eyes that underwent cataract surgery.

The standard deviation in the rate of refractive growth of normal eyes in our study is half of that found in eyes that underwent cataract surgery.

To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of incisional goniotomy as an adjunct to phacoemulsification in primary angle-closure glaucoma (PACG) patients.

In this prospective interventional case series, consecutive patients with PACG (high or borderline IOP) deemed fit for phacoemulsification were enrolled. Following phacoemulsification, incisional goniotomy was performed with or without goniosynechialysis. check details Patient demographic profile, clinical data, and adverse events, if any, were analysed during at least a 6-month follow-up period. Success was defined as IOP ≤ 18 mm Hg with or without medications.

Of 46 eyes (38 patients), 69.6% eyes were classified as having advanced glaucoma. Mean treated IOP decreased by 7.3±1 (SE) mmHg (95% CI 5.2- 9.3) from 21.4±6.6 to 14.2±3.7 mmHg at mean duration of 11.7±5.5 months (6-22 months) postoperatively (P< 0.001; paired t test). There was 66.6% reduction in median number of hypotensive medications (P<0.001; Wilcoxon Signed rank test). Observed complications included hyphema (28%;13 eyes), IOP spike (6.5%; 3 eyes) and cyclodialysis (2.17%; 1 eye). High treated IOP and number of medications were significantly associated with failure in univariate analysis (p<0.05; Fisher exact test). The cumulative survival probability for qualified success at 22 months was 87.8%±0.07 (95% CI0.65-0.96).

Incisional goniotomy as an adjunct with phacoemulsification resulted in a significant and sustained reduction in IOP along with decrease in number of glaucoma medications in chronic PACG eyes, irrespective of the disease stage.

Incisional goniotomy as an adjunct with phacoemulsification resulted in a significant and sustained reduction in IOP along with decrease in number of glaucoma medications in chronic PACG eyes, irrespective of the disease stage.

To detect keratoconus using optical coherence tomography (OCT) corneal map parameters and patterns.

Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA DESIGN Cross-sectional observational study.

A spectral-domain OCT was used to acquire corneal and epithelial thickness maps in normal, manifest keratoconic, subclinical keratoconic, and forme fruste keratoconic (FFK) eyes. A two-step decision tree was designed. An eye will be classified as keratoconus if both decision tree conditions are met First, at least one of the four quantitative corneal thickness (minimum, minimum-maximum, superonasal-inferotemporal) and epithelial thickness (standard deviation) map parameters exceed cutoff values. Second, presence of both concentric thinning pattern on the epithelial thickness map and coincident thinning patterns on corneal and epithelial thickness maps by visual inspection.

The study was compromised of 54 eyes from 29 normal participants, 91 manifest keratoconic eyes from 65 patients, 12 subclinical keratoconic eyes from 11 patients, and 19 FFK eyes from 19 patients. The decision tree correctly classified all normal eyes (100% specificity), and had good sensitivities for detecting manifest keratoconus (97.8%), subclinical keratoconus (100.0%), and FFK (73.7%).

The two-step decision tree provided a useful tool to detect keratoconus including cases at early disease stages (subclinical keratoconus and FFK). OCT corneal and epithelial thickness map parameters and patterns can be used in conjunction with topography to improve keratoconus screening.

The two-step decision tree provided a useful tool to detect keratoconus including cases at early disease stages (subclinical keratoconus and FFK). OCT corneal and epithelial thickness map parameters and patterns can be used in conjunction with topography to improve keratoconus screening.

To assess if small-incision lenticule extraction (SMILE) for high myopia reduces the binocular visual function assessed by stereoacuity, binocular visual acuity, binocular contrast sensitivity, and binocular summation.

University hospital DESIGN Prospective case series METHODS Patients with a myopic spherical equivalent of at least 6 diopters (D) scheduled for SMILE aimed at emmetropia were included. Psychophysical testing was done with correction before surgery but no correction after surgery. Stereoacuity was assessed with the Randot Circles test and the near Frisby test, visual acuity (monocular and binocular) was assessed with high-contrast Early Treatment Diabetic Retinopathy Study charts, and contrast sensitivity (monocular and binocular) was assessed with the Pelli-Robson chart and the Freiburg Acuity and Contrast Test. Binocular summation was calculated by comparing the binocular score against the best monocular score.

138 eyes of 69 patients were included. Mean spherical equivalent changed from -7.46 D±1.06 (SD) to -0.23 D±0.40 after surgery. Stereoacuity did not change significantly following surgery; median change (IQR) was -0.32 (-6.21 to 1.55) seconds of arc with the Frisby test and 0.00 (-7.5 to 5.0) seconds of arc with the Randot test (P≥0.06). Binocular postoperative uncorrected distance visual acuity was not different from the preoperative corrected distance visual acuity (P=0.40). Contrast sensitivity declined slightly monocularly with both tests of contrast sensitivity, but was unaltered binocularly (P≥0.08). Binocular summation for visual acuity and contrast sensitivity was unaltered following surgery (P≥0.09).

SMILE for high myopia did not reduce the binocular function assessed by stereoacuity, binocular visual acuity, binocular contrast sensitivity, and binocular summation.

SMILE for high myopia did not reduce the binocular function assessed by stereoacuity, binocular visual acuity, binocular contrast sensitivity, and binocular summation.