These results suggest that rtPCR and IHC are promising techniques that can be used in FFPE tissues to detect B. canis when other detection techniques are unavailable. Additionally, accurate recognition of epididymitis rather than orchitis in suspect cases could aid in accurate diagnosis.Clear vision is dependent on features that protect the anatomical integrity of the eye (cornea and sclera) and those that contribute to internal ocular homeostasis by conferring hemangiogenic (avascular tissues and antiangiogenic factors), lymphangiogenic (lack of draining lymphatics), and immunologic (tight junctions that form blood-ocular barriers, immunosuppressive cells, and modulators) privileges. The later examples are necessary components that enable the eye to maintain an immunosuppressive environment that responds to foreign invaders in a deviated manner, minimizing destructive inflammation that would impair vision. These conditions allowed for the observations made by Medawar, in 1948, of delayed rejection of allogenic tissue grafts in the anterior chamber of mouse eye and permit the sequestration of foreign invaders (eg, Toxoplasma gondii) within the retina of healthy individuals. Yet successful development of intraocular drugs (biologics and delivery devices) has been stymied by adverse ocular pathology, much of which is driven by immune pathways. The eye can be intolerant of foreign protein irrespective of delivery route, and endogenous ocular cells have remarkable plasticity when recruited to preserve visual function. This article provides a review of current understanding of ocular immunology and the potential role of immune mechanisms in pathology observed with intraocular drug delivery.Resilience is critical among survivors of trafficking as they are mostly vulnerable populations who face multiple adversities before, during, and after trafficking. However, resilience in survivors of trafficking is understudied. This scoping review aims to clarify the current state of knowledge, focusing on definitions of resilience, how resilience has been studied, and factors associated with resilience among survivors. Five databases were searched using key words related to trafficking and resilience. Studies were included if they were published in English between 2000 and 2019 and focused on resilience with the study design including at least one of these four features (a) use of standardized measures of resilience, (b) qualitative descriptions of resilience, (c) participants were survivors or professionals serving survivors, and (d) data sources such as case files or program manuals directly pertained to survivors. Eighteen studies were identified. Findings indicated that resilience was primarily described as emergent from interactions between the survivor and the environment. Selleck Alvocidib Resilience in trafficking appeared largely similar to resilience in other kinds of victimization. Nonetheless, trafficking survivors also may display resilience in alternative ways such as refusing treatment. Positive interpersonal relationships were the most commonly mentioned resilience factor. In addition, current research lacks studies featuring longitudinal designs, interventions, participatory methods, types of trafficking other than sexual trafficking, and demographic characteristics such as age, gender, and national origin. Future research needs to establish definitions and measures of resilience that are culturally and contextually relevant to survivors and build knowledge necessary for designing and evaluating resilience-enhancing interventions.The purpose of this scoping review is to provide a timely update of available research describing parents’ perspectives of parenting pre-teen children of Generation Z (born 1997 through 2012). The databases of Ovid MEDLINE, CIHAHL, SCOPUS, Web of Science, JUSTOR, and PsyINFO were searched using a combination of key words for manuscripts published in English. A limited collection of scientific literature documented experiences of parents, practices of parenting, styles of parenting, and interventions that influence parenting of Generation Z pre-teen children among various groups of parents. Although an emerging body of literature on parenting pre-teen children of Generation Z was identified, future research should consider systematic sample selection to further explore the roles of cultural and psychosocial factors that influence parents’ perspectives of parenting “digital natives” in homes around the world.Teen dating violence (TDV) affects millions of youth in the United States and globally each year. A systematic review was conducted to examine the help-seeking intentions and behaviors of youth between the ages of 12 and 19 based on racial and ethnic differences. Considering the high prevalence of TDV among racially and ethnically diverse youth, previous systematic reviews have recommended that future scholarship address help-seeking intentions and behaviors among racially and ethnically diverse youth. The methodologies and results of TDV and help-seeking studies published since 2000 were reviewed and analyzed. A systematic search of peer-reviewed journal articles published in English was conducted using an electronic search. The rigorous search identified 10 studies that addressed help-seeking intentions and behaviors and racial and ethnic differences in youth meeting eligibility requirements. The search yielded few studies, indicating a need to conduct future research in this area. The strength of the studies’ methodologies limited generalizability and external validity. The studies primarily addressed differences among African American and Latino youth. Youth relied on informal sources of support, with youth from both groups preferring to seek help from parents and friends. Mistrust, lack of closeness, and feelings of mistrust, shame, and embarrassment informed youths’ help-seeking intentions and behaviors. Racially and ethnically specific factors such as negative perceptions of father figures, familism, acculturation, and traditional gender role notions were identified as barriers to help-seeking. As part of appraising and synthesizing the evidence, recommendations for research, practice, and policy are presented.