These compounds displayed IC50 values in nanomolar range against A549, MCF7, PC3 and HCT116 cell outlines, deducing the development that piperazine or 4-aminopiperidine is the linker’s best choice to produce EA analogs with highly powerful anti-proliferative activities own up to 24 nM. Besides, when it comes to selectivity, those linkers are more…[Read more]