In inflammatory and tumor lesions of the PSG multidirectional differences are noted in the ratio between the concentrations of pro- and anti-inflammatory mediators in the oral fluid. In chronic sialadenitis of PSG in the oral fluid a moderate increase in the levels of IL-6 and IL-10 occurs, in the presence of adenoma of PSG, the concentration of IL-6 does not change while IL-10 increases threefold, and there is a sharp and unidirectional increase in the concentration of cytokines of the opposite groups in case of a malignant lesion of PSG.

Comparison of the concentration of IL-6 and IL-10 in saliva and their ratio defined by the developed discriminant models helps to make an individual diagnostic decision in a specific clinical situation.

Comparison of the concentration of IL-6 and IL-10 in saliva and their ratio defined by the developed discriminant models helps to make an individual diagnostic decision in a specific clinical situation.

To compare dental and psychological status in athletes of Olympic teams and the population of Moscow.

In order to study the features of the dental rehabilitation of Olympic athletes, a comparative study of the dental and psychological status of 132 athletes was carried out when they were included in the Olympic teams and 104 residents of Moscow of the same age. Clinical x-ray examination was supplemented by «Hamburg testing» of the masticatory apparatus and psychological examination using common questionnaires and scales.

The study revealed a difference in the status of dental status, the results of the “Hamburg Testing” and psychological examination between athletes of the Olympic reserve and the population of Moscow of the same age. Athletes showed a lower quality of previous treatment of caries and its complications, insufficient oral hygiene, more frequent detection of chronic periodontitis, diseases of the oral mucosa, secondary deformations of the dentition, pathological phenomena of the temporomandibular joint, masticatory apparatus dysfunction according to the results of the “Hamburg Testing”. Athletes also established psychological status features higher rates of reactive and personal anxiety, the presence of depressive manifestations, lower quality of sleep and quality of life.

The revealed patterns can provoke muscle hyper-tone and muscular-articular dysfunction of the maxillofacial region, which must be taken into account during the dental rehabilitation of athletes of Olympic teams.

The revealed patterns can provoke muscle hyper-tone and muscular-articular dysfunction of the maxillofacial region, which must be taken into account during the dental rehabilitation of athletes of Olympic teams.

The study investigated the effect of 2%s odium hypochlorite gel application after post-etching salivary contamination on composite bonding strength to primary teeth enamel.

The sample consisted of 79 primary human teeth that were extracted no more than one month ago. The sample was randomly divided into four groups (1) the control group (A) comprised 10 primary teeth, and composites were applied in the traditional manner without any salivary contamination; (2) the second group (B) consisted of 23 primary teeth in which salivary contamination was conducted after etching followed by re-etching and follow-up; (3) the third group (C) comprised 23 primary teeth in which saliva contamination was done after etching followed by washing, drying, and follow-up; and (4) the fourth group (D) comprised 23 primary teeth, in which salivary contamination was conducted after etching followed by application of sodium hypochlorite gel and follow-up. The samples were tested using the Testometric Tensile Strength Device (Testometric M350-10 kN, Testometric Ltd., UK) to measure the composite bonding strength to enamel of primary teeth.

The arithmetic mean strength values in the research sample were ordered as followed (A=13.39 MPa) > (D=11.82 MPa) > (C=8.07 MPa) > (B=6.15 MPa). The application of sodium hypochlorite gel after salivary contamination significantly improved the composite bonding strength to primary teeth enamel when compared with re-etching or only washing and drying.

15 s exposition of sodium hypochlorite gel with subsequent rinse and drying is recommended in case of saliva contamination of etched primary tooth enamel surface.

15 s exposition of sodium hypochlorite gel with subsequent rinse and drying is recommended in case of saliva contamination of etched primary tooth enamel surface.

To study the features of reparative dentinogenesis when using biomaterials during accidental opening of the pulp in an experiment.

In an experiment on 3 dwarf pigs of the Svetlogorsk breed a traumatic opening of the tooth cavity was carried out in 18 teeth (6 molars, 6 premolars, 6 incisors), then Biodentin (9 teeth) and Aurosil (9 teeth) were applied on the opened pulp horn. ON-01910 in vivo After 14, 30 and 60 days, dwarf pigs were euthanized, and jaw blocks taken. Histological examination of the teeth was carried out using the method of embedding in methyl methacrylate (OsteoBead, Sigma, USA). Thin sections of 35-50 microns were made from the samples and stained using the «Heavenly Trichrome» method. Documentation was carried out using a Leica DM100 microscope and an EC3 digital camera in reflected and transmitted light.

Histological examination of the thin sections of teeth stained according to the «Heavenly Trichrome» method revealed that 2 weeks after the pulp opening and applying of Aurosil and Biodentin, comparable processes occurred in the tooth cavity. Thus, the proliferation of odontoblasts was noted on the lateral surfaces of the chamber. New dentin layers and odontoblasts spread over the lower surface of the material with the formation of dentinal bridges by 4 weeks of observation in both groups. By week 12, there was a decrease in the proliferative activity of odontoblasts and dentin maturation in all cases. At the initial stages of the experiment, some pulp edema and moderate plethora were noted, which was no longer observed at 4 weeks. By 12 weeks, because of the proliferation of odontoblasts, the volume of the tooth cavity was reduced by a third. By the 6th month in the experiment, no significant changes in the structure of dentin and pulp were revealed.

According to morphological data the studied biomaterials (Aurosil and Biodentin) contribute to dentin regeneration equally.

According to morphological data the studied biomaterials (Aurosil and Biodentin) contribute to dentin regeneration equally.