Before the intervention, infants under two months had a higher risk of getting pertussis in comparison with infants two to six months old (HR 1.15, CI 95% 1.11-1.19). After the intervention, age under two months is a protective factor compared with two to six months (HR 0.90, CI 95% 0.82-0.98). BAY-61-3606 The pertussis incidence reduced in all age groups and all Brazil’s Regions.

Patients with adverse spinopelvic mobility have higher complication rates following total hip arthroplasty (THA). Risk factors include a stiff lumbar spine, standing posterior pelvic tilt ≤-10°, and a severe sagittal spinal deformity (pelvic incidence minus lumbar lordosis mismatch ≥20°). The purpose of this study is to define the spinopelvic risk factors and quantify the prevalence of risk factors for pathologic spinopelvic mobility.

A retrospective cohort analysis from January 2014 to February 2020 was performed on a multicenter series of 9414 primary THAs by 168 surgeons, all with preoperative spinopelvic measurements in the supine, standing, and flex-seated positions. All patients were included. The prevalence of adverse spinopelvic mobility and frequency of each spinopelvic risk factor was calculated.

The cohort was 52% female, 48% male, with an average age of 65 years. Thirteen percent of patients exhibited adverse spinopelvic mobility and 17% had one or more of the 3 risk factors. Adverse mobility was found in 35% of patients with at least 1 risk factor, 47% with at least 2 risk factors, and 57% with all 3 risk factors.

Forty-six percent of patients had spinopelvic pathology driven by one or more of the risk factors. Number of risk factors present and risk of adverse spinopelvic mobility were positively correlated, with 57% of patients with all 3 risk factors exhibiting adverse spinopelvic mobility. Although this study defines the prevalence of these risk factors in this highly selected cohort, it does not report incidence in a general THA population.

Prognostic Level IV.

Prognostic Level IV.

The growing recognition of prehabilitation has caused an emerging paradigm shift in surgical cancer care and an integrated component of the cancer care continuum. This narrative review aims to update and inform the urological community of the potential of prehabilitation before radical cystectomy.

A nonsystematic narrative review was performed through a database search in PubMed, and CINAHL using the following search terms enhanced recovery after surgery (ERAS); Frailty; Prehabilitation and/or Rehabilitation; Physical Activity and/or exercises; Nutrition; Nutritional Care; Smoking cessation; Alcohol cessation; Prevention; Supportive Care; and combined with Radical Cystectomy.

A multimodal and multi-professional approach during the preoperative period may offer an opportunity to preserve or enhance physiological integrity and optimize surgical recovery. Studies indicate a positive effect of prehabilitation on postoperative functional capacity and earlier return to daily activities and health related qualional capacity. The growing movement to standardize clinical implementation of prehabilitation, indicate there is a clear need for further investigation, optimization of a multimodal approach and an open discussion between health care providers from different areas of expertise who might best support and promote these initiatives.Neutropenic enterocolitis is also known as typhlitis, is characterized by severe inflammation in the bowel loops. It is often seen in immunosuppressed patients, and it has high morbidity and mortality. Although the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory system and causes COVID-19 (Coronavirus Disease 2019), it may affect hematopoietic and gastrointestinal systems. Herein, we present a rare case of COVID-19-associated pancytopenia and typhlitis in a 60-year-old female who presented with abdominal pain. Contrast-enhanced abdominal computed tomography (CT) demonstrated the bowel wall thickening in the cecum and ascending colon compatible with enterocolitis. Moreover, the chest CT showed bilateral, peripheral, and multifocal ground-glass opacities, consistent with COVID-19 pneumonia. We also aimed to emphasize the laboratory, clinical, and CT findings of the patient.

Coronary Artery disease (CAD) accounts for one-third or more of all deaths in individuals over 35 years of age. In Ayurveda, umbrella term Hrdroga encompasses the concept of CAD. Vegadharana, suppression of natural urges is a lifestyle error that has been denoted as a potential risk factor of Hrdroga, but there is a lacuna of convincing research works.

The present study is designed to assess and evaluate the association of Purisavegadharana, Baspavegadharana (bowel, tear suppression) with CAD.

Study followed case-control design; Cases (110) were patients aged above 18 years of either sex, diagnosed with CAD in a duration less than or equal to 10 years, attending outpatient department (OPD) of an Allopathy and Ayurveda hospital. The controls (110) included hospital controls from same hospitals. Exposure status was assessed through Case Record Form (CRF), Bowel suppression and Tear suppression assessment Questionnaires, interview with patients and scrutiny of past medical records. Odds ratios and chi-square tests were computed. Receiver Operating Characteristic (ROC) curves of logistic regression models fitted were generated and optimal cut-off points for bowel and tear suppression scores were derived through Youden index.

Tear suppression and bowel suppression showed odds ratio of 4.47 and 2.30 respectively. Other commendable predisposing factors were age above 60 years, family history of disease and use of medication. Highest odds ratio from logistic regression was for palpitation (8.67) and followed by tobacco use (6.23).

Study indicated high association of bowel and tear suppression with CAD along with other predisposing factors, prominent of which were palpitation and use of tobacco use.

Study indicated high association of bowel and tear suppression with CAD along with other predisposing factors, prominent of which were palpitation and use of tobacco use.