Lung ultrasonographic (LUS) imaging may play an important role in the management of patients with COVID-19-associated lung injury, particularly in some special populations. However, data regarding the prognostic role of the LUS in nursing home residents, one of the populations most affected by COVID-19, are not still available.

Retrospective.

Nursing home residents affected by COVID-19 were followed up with an LUS from April 8 to May 14, 2020, in Chioggia, Venice.

COVID-19 was diagnosed through a nasopharyngeal swab. LUS results were scored using a 12-zone method. For each of the 12 zones (2 posterior, 2 anterior, 2 lateral, for both left and right lungs), the possible score ranged from 0 to 3 (1=presence of B lines, separated, with <50% of space from the pleural line; 2=presence of B lines, separated, with >50% of space from the pleural line; 3=lung thickening with tissuelike aspect). The total score ranged from 0 to 36. Mortality was assessed using administrative data. Data regarding accuracy available only in hospital.We report a case of blood exchange transfusion to treat acute liver failure following hepatitis B infection at the Infectious Disease Department of Children’s Hospital No.2 in Ho Chi Minh City, Vietnam. A 3.5-month old baby boy was admitted to the hospital with a presentation of progressively worsening jaundice for the past one month. The patient was diagnosed with hepatitis B infection with a positive HBV DNA quantitative assay. Plasma exchange was indicated in view of progressive liver failure and gradually increasing hepatic coma. However, it was impossible to perform plasmapheresis in this case because the patient was small (in terms of age and weight) and there was no suitable plasma exchange filter. Accordingly, the patient was treated with 3 times of blood exchange transfusion in combination with an antiviral drug, lamivudine. After each blood exchange transfusion, the biochemical values (bilirubin, liver enzymes, and coagulation profile) gradually improved and he was discharged after 1 month of treatment. Blood exchange transfusion is an effective procedure for managing acute liver failure, where plasma exchange is not possible while waiting for the recovery of liver functions or liver transplantation.SARS-CoV-2 has infected millions worldwide. The virus is novel, and currently there is no approved treatment. Convalescent plasma may offer a treatment option. We evaluated trends of IgM/IgG antibodies/plasma viral load in donors and recipients of convalescent plasma. 114/139 (82 %) donors had positive IgG antibodies. 46/114 donors tested positive a second time by NP swab. Among those retested, the median IgG declined (p  less then  0.01) between tests. 25/139 donors with confirmed SARS-CoV-2 were negative for IgG antibodies. This suggests that having had the infection does not necessarily convey immunity, or there is a short duration of immunity associated with a decline in antibodies. Plasma viral load obtained on 35/39 plasma recipients showed 22 (62.9 %) had non-detectable levels on average 14.5 days from positive test versus 6.2 days in those with detectable levels (p  less then  0.01). There was a relationship between IgG and viral load. IgG was higher in those with non-detectable viral loads. There was no relationship between viral load and blood type (p = 0.87) or death (0.80). Recipients with detectable viral load had lower IgG levels; there was no relationship between viral load, blood type or death.

In 2018, Trima Accel software version 6.4 with autoflow management released in China. The purpose of this retrospective study was to evaluate the effects of autoflow management on plateletpheresis procedures, specifically concerning flow-rate alerts, collection efficiency (CE), and collection rate (CR).

A total of 2526 procedures using Trima Accel version 6.4 from Nov 2018 to Jan 2019 were included as the test arm in this study. Another 2043 procedures using version 5.1.9 from Nov 2017 to Jan 2018 were included as the control arm. We compared the low-flow alerts and no-flow alerts, collection efficiency (CE), and collections rate (CR) between the two study arms. Also, we analyzed the incidence of autoflow increases and autoflow decreases of version 6.4.

The incidence of low-flow alerts for test and control was 16.6 % and 55.3 %(χ

= 754.024, p = 0.000), with the maximum number of low-flow signals of 6 and 51, respectively. The incidence of no-flow alerts for test and control was 7.8 % and 45.0 %(χ

= 843.695, p = 0.000), with a maximum of 16 and 27, respectively. The CE of version 6.4 was slightly higher than version 5.1.9 (69.7 ± 6.7 % versus 68.6 ± 7.4 %). Similarly, CR was higher for version 6.4 (7.7 ± 2.1versus 7.0 ± 1.8 × 10

/min). Selleck Ipatasertib For software version 6.4, autoflow increases or autoflow decreases triggered in 99.8 % donors.

Autoflow management shows significant advantages in reducing alerts and subsequent manual intervention. We observe a higher CR and CE using Trima Accel version 6.4 than version 5.1.9, which leads to a more efficient platelet collection.

Autoflow management shows significant advantages in reducing alerts and subsequent manual intervention. We observe a higher CR and CE using Trima Accel version 6.4 than version 5.1.9, which leads to a more efficient platelet collection.

There are two surgical approaches to reconstruct a pressure ulcer (PU) one-stage reconstruction or two-stage reconstruction. One stage reconstruction consists of surgical debridement and flap reconstruction during one operation. Two-stage surgery consist of a surgical debridement and a final reconstruction in two different sessions, with approximately six weeks between both sessions.

The aim of this study was to compare the results of single stage surgery and two-stage surgery on the PU recurrence rate and other important post operative complications.

A retrospective, comparative study in Spinal Cord Injured (SCI) individuals with a single- or two stage surgical reconstruction between 2005 and 2016 was designed. A total of 81 records were included for analysis.

The primary outcome, the difference in occurrence of a recurrent PU in the reconstructed area (33.3% versus 31.6%), is not statistically significant between one-and two-stages reconstruction. Also, the mean duration to develop a recurrent PU between both surgical reconstructions is not statistically significant.